Furosemide solvates: can they serve as precursors to different polymorphs?

Chatbots: Can They Serve as Natural Language Interfaces to Qa Corpus?

A chatbot is a program which can chat in natural language, on a topic built into the chatbot’s internal knowledge model. Many chatbots exist, with different knowledge-bases programmed by the chatbot builders. We have built a system to convert a website text (corpus) to a chatbot knowledge-base format. In this paper the chatbot is used as a question answer interface, where TRE09 QA track is used...

How Can Bee Colony Algorithm Serve Medicine?

Healthcare professionals usually should make complex decisions with far reaching consequences and associated risks in health care fields. As it was demonstrated in other industries, the ability to drill down into pertinent data to explore knowledge behind the data can greatly facilitate superior, informed decisions to ensue the facts. Nature has always inspired researchers to develop models of ...

How Long Do They Serve?

Polymorphs, hydrates and solvates of a co-crystal of caffeine with anthranilic acid.

A polymorph screen on a new 1:1 co-crystal of caffeine, C8H10N4O2, with anthranilic acid, C7H7NO2, has revealed a rich diversity of crystal forms (two polymorphs, two hydrates and seven solvates, including two sets of isostructural solvates). These forms were prepared by liquid-assisted grinding and solution crystallization, and the crystal structures of nine of these forms have been solved usi...

High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids.

The concepts of high-throughput (HT) screening and combinatorial synthesis have been integrated into the pharmaceutical discovery process, but are not yet commonplace in the pharmaceutical development arena. Emerging strategies to speed pharmaceutical development and capture solid form diversity of pharmaceutical substances have resulted in the emergence of HT crystallization technologies. The ...